Clinical Trials

Where can I find information about clinical trials of targeted therapies?

The list below provides links to active clinical trials of FDA-approved targeted therapies. Because trials begin and end regularly, it is possible that, at any given time, a particular drug will not have any trials available. If you are viewing this fact sheet online (http://www.cancer.gov/cancertopics/factsheet/Therapy/targeted), the drug names are links to search results for trials in NCI’s clinical trials database. This database can also be searched on NCI’s Web site by visiting http://www.cancer.gov/clinicaltrials/search. For information about how to search the database, see “Help Using the NCI Clinical Trials Search Form” at http://www.cancer.gov/clinicaltrials/search-form-help. The database includes all NCI-funded clinical trials and many other studies conducted by investigators at hospitals and medical centers in the United States and other countries around the world.

Targeted Cancer Therapies Being Studied in Clinical Trials:

  • Alemtuzumab (Campath®)
  • Alitretinoin (Panretin®)
  • Anastrozole (Arimidex®)
  • Bevacizumab (Avastin®)
  • Bexarotene (Targretin®)
  • Bortezomib (Velcade®)
  • Cetuximab (Erbitux®)
  • Dasatinib (Sprycel®)
  • Denileukin diftitox (Ontak®)
  • Erlotinib hydrochloride (Tarceva®)
  • Everolimus (Afinitor®)
  • Exemestane (Aromasin®)
  • Fulvestrant (Faslodex®)
  • Gefitinib (Iressa®)
  • Ibritumomab tiuxetan (Zevalin®)
  • Imatinib mesylate (Gleevec®)
  • Lapatinib ditosylate (Tykerb®)
  • Letrozole (Femara®)
  • Nilotinib (Tasigna®)
  • Ofatumumab (Arzerra®)
  • Panitumumab (Vectibix®)
  • Pazopanib hydrochloride (Votrient®)
  • Pralatrexate (Folotyn®)
  • Rituximab (Rituxan®)
  • Romidepsin (Istodax®)
  • Sorafenib tosylate (Nexavar®)
  • Sunitinib malate (Sutent®)
  • Tamoxifen
  • Temsirolimus (Torisel®)
  • Toremifene (Fareston®)
  • Tositumomab and 131I-tositumomab (Bexxar®)
  • Trastuzumab (Herceptin®)
  • Tretinoin (Vesanoid®)
  • Vorinostat (Zolinza®)
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